Dusp5 negatively regulates IL ‐33‐mediated eosinophil survival and function
نویسندگان
چکیده
منابع مشابه
Dusp5 negatively regulates IL-33-mediated eosinophil survival and function.
Mitogen-activated protein kinase (MAPK) activation controls diverse cellular functions including cellular survival, proliferation, and apoptosis. Tuning of MAPK activation is counter-regulated by a family of dual-specificity phosphatases (DUSPs). IL-33 is a recently described cytokine that initiates Th2 immune responses through binding to a heterodimeric IL-33Rα (ST2L)/IL-1α accessory protein (...
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ژورنال
عنوان ژورنال: The EMBO Journal
سال: 2014
ISSN: 0261-4189,1460-2075
DOI: 10.15252/embj.201489456